Select Publications
Ma R, Gong D, You H, Xu C, Lu Y, Bergers G, Werb Z, Klein OD, Petritsch CK, Lu P. LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland. Cell Rep. 2022 Feb 15;38(7):110375. PMID: 35172155.
Lu Y, Zhou T, Xu C, Wang R, Feng D, Li J, Wang X, Kong Y, Hu G, Kong X, Lu P. Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR. PLoS Biol. 2022 Jan 18;20(1):e3001518.PMID: 35041644
Lu Y, Deng R, You H, Lu P. 3D in vitro culture system to study collective migration in mammary organoid epithelium. STAR Protoc. 2021 Aug 27;2(3):100778. PMID: 34485944
Lu P, Lu Y. Born to Run? Diverse Modes of Epithelial Migration. Front Cell Dev Biol. 2021 Aug 12;9:704939. PMID: 34540829
Lu Y, Deng R, You H, Xu Y, Antos C, Sun J, Klein OD, Lu P. Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium. Cell Rep. 2020 Oct 13;33(2):108246. PMID: 33053348
Zhang Z, Sun W, Shi T, Lu P, Zhuang M, Liu JL. Capturing RNA-protein interaction via CRUIS. Nucleic Acids Res. 2020 May 21;48(9):e52. PMID: 32140725
Zhou T, Lu Y, Xu C, Wang R, Zhang L, Lu P. Occludin protects secretory cells from ER stress by facilitating SNARE-dependent apical protein exocytosis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4758-4769. PMID: 32051248
Shi T, Yao L, Han Y, Hao P, Lu P. Quantitative Phosphoproteomics Reveals System-Wide Phosphorylation Network Altered by Spry in Mouse Mammary Stromal Fibroblasts. Int J Mol Sci. 2019 Oct 30;20(21):5400. PMID: 31671542
Lu P, Zhou T, Xu C, Lu Y. Mammary stem cells, where art thou? Wiley Interdiscip Rev Dev Biol. 2019 Nov;8(6):e357. PMID: 31322329.
Koledova Z, Lu P. A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol. 2017;1501:217-231. PMID: 27796955.
Yao L, Lu P, Ling EA. Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia. PLoS One. 2016 Nov 3;11(11):e0166010. PMID: 27812200
Koledova Z, Zhang X, Streuli C, Clarke RB, Klein OD, Werb Z, Lu P. SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5731-40. PMID: 27621461
Werb Z, Lu P. The Role of Stroma in Tumor Development. Cancer J. 2015 Jul-Aug;21(4):250-3. PMID: 26222075
Zhang X, Martinez D, Koledova Z, Qiao G, Streuli CH, Lu P. FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis. Development. 2014 Sep;141(17):3352-62. Epub 2014 Jul 30. PMID: 25078648
Zhang X, Qiao G, Lu P. Modulation of fibroblast growth factor signaling is essential for mammary epithelial morphogenesis. PLoS One. 2014 Apr 9;9(4):e92735. PMID: 24718286
Howard BA, Lu P. Stromal regulation of embryonic and postnatal mammary epithelial development and differentiation. Semin Cell Dev Biol. 2014 Jan-Feb;25-26:43-51. PMID: 24445189
Kim EJ, Jung HS, Lu P. Pleiotropic functions of fibroblast growth factor signaling in embryonic mammary gland development. J Mammary Gland Biol Neoplasia. 2013 Jun;18(2):139-42. PMID: 23613170
Lu P, Weaver VM, Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol. 2012 Feb 20;196(4):395-406. PMID: 22351925
Lu P, Takai K, Weaver VM, Werb Z. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol. 2011 Dec 1;3(12):a005058. PMID: 21917992
Lu P, Werb Z. Patterning mechanisms of branched organs. Science. 2008 Dec 5;322(5907):1506-9. PMID: 19056977
Lu P, Ewald AJ, Martin GR, Werb Z. Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. Dev Biol. 2008 Sep 1;321(1):77-87. PMID: 18585375
Lu P, Yu Y, Perdue Y, Werb Z. The apical ectodermal ridge is a timer for generating distal limb progenitors. Development. 2008 Apr;135(8):1395-405. PMID: 18359901
Lu P, Sternlicht MD, Werb Z. Comparative mechanisms of branching morphogenesis in diverse systems. J Mammary Gland Biol Neoplasia. 2006 Oct;11(3-4):213-28. PMID: 17120154
Sternlicht MD, Kouros-Mehr H, Lu P, Werb Z. Hormonal and local control of mammary branching morphogenesis. Differentiation. 2006 Sep;74(7):365-81. PMID: 16916375
Lu P, Minowada G, Martin GR. Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function. Development. 2006 Jan;133(1):33-42. PMID: 16308330.
